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Key mechanisms of action include: AMPK activation – Berberine appears to activate adenosine monophosphate-activated protein kinase (AMPK), an enzyme that regulates cellular energy metabolism

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Among these, PYY, a hormone secreted by intestinal L cells, circulates in two principal bioactive forms: PYY(1-36) and PYY(3-36), which exhibit distinct receptor affinities and physiological roles (3)