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A diferencia del GLP-1, el GIP aumenta la secreción de glucagón por las células alfa, estimula la lipogénesis, inhibe la lipólisis en los adipocitos y mejora la captación de ácidos grasos 4
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Wegovy is dosed higher (up to 2.4 mg vs 1.0 mg for diabetes), which produces more weight loss and proportionally more bone density reduction