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It was shown that the NKG2A and PD-L1 expression group was positively correlated with more immune cell infiltration (CD8 + T cells, B cells, M1 macrophages, and NK cells) and inflammatory factors (IFN-γ, GZMB, and PRF-1), which implies that NKG2A and PD-L1 expression is not only associated with the tumor microenvironment but also with the inflammatory microenvironment

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“This landmark study builds on more than 20 years of research in obesity, a serious chronic disease associated with severe co-morbidities and outcomes,” Martin Langue, executive vice president and head of development at Novo Nordisk, said in a statement