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Tirzepatide is primarily excreted by the kidneys, so reduced renal function could theoretically affect its pharmacokinetics and efficacy ( 2 ) indicated that reduced renal function does not significantly alter the exposure or glycemic effects of tirzepatide ( Finally, there may be differences in drug metabolism, absorption, and tolerance among different ethnic groups, which may affect the efficacy and safety of tirzepatide
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It's also important to consider alternative causes of cognitive symptoms, such as anaemia, sleep apnoea, depression, thyroid disease, or vitamin B12 deficiency (which can occur with long-term metformin use)
approved for chronic weight management when used with diet and exercise
