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ada glp-1 guidelines dpp4 and glp 1 FIGURE 4, [Choosing glucose-lowering medication for patients...] Today, the American Diabetes Association® –
GLP-1 is a major incretin that promotes glucose-dependent insulin secretion from pancreatic beta cells and decreases glucose-dependent glucagon secretion from alpha cells, thereby increasing glucose uptake in peripheral tissues and inhibiting gluconeogenesis in the liver [70–72]
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Two active forms of GLP-1 are generated in the gut and brain: active GLP-1 (7-36) amide and active GLP-1 (7-37) non-amide 10
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