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4.3 The critical need for biomarkers of brain ferroptosis in vivo The advancement of ferroptosis-targeted therapies in clinical trials is hampered by a critical bottleneck: the absence of validated, non-invasive biomarkers to directly detect and monitor ferroptosis within the brains of living patients
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The SLIM LIVER trial (ACTG A5371), also funded by the NIH, enrolled 51 adults on suppressive antiretroviral therapy with a large waist circumference, insulin resistance or pre-diabetes and MASLD
