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Surface-mediated spontaneous emulsification of the acylated peptide, semaglutide [PMID: 38227645] Laboratory literature summary: Surface-mediated spontaneous emulsification of the acylated peptide, semaglutide

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In addition, we show that a membrane-attached GLP-1R ECD can mediate hormone activation of the GLP-1R TMD in trans, suggesting a direct GLP-1R ECD-TMD interaction as a mechanistic requirement for receptor activation