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While the primary use of semaglutide is for the treatment of type 2 diabetes and obesity, its impact on weight loss and metabolic health may offer indirect benefits for women with PCOS, such as the improvement of insulin sensitivity and potential amelioration of PCOS symptoms

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Preclinical research suggests potential additive effects on beta-cell function and synergistic effects on food intake and energy expenditure compared to GLP-1 agonism alone