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2 GLP-1 Lys 26 may form a polar interaction with the receptor, which is presumably enhanced by Arg 20 in exenatide, but creates no steric hindrance
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Neuronal/endocrine factors affecting the intestinal release of PGDPs in some species include GIP, acetylcholine, gastrin-releasing peptide (GRP), insulin, somatostatin, and ghrelin [[320], [321], [322]]
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