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7 Special consideration should be given to medications that have a narrow therapeutic index and in individuals with kidney dysfunction
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Pica test serves as an indirect indicator of nausea/malaise in non-vomiting species (e.g., mice), assessed through the ingestion of kaolin clay, a non-nutritive substance that mice instinctively consume as a response to gastrointestinal discomfort 77
while others have faced adverse effects like Constipation and increased hunger
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