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Weight loss may occur during treatment, but semaglutide is not intended to replace appropriate nutrition, physical activity or continuing medical care.(2 ✔ ✔Trusted Source WHO issues global guideline on the use of GLP-1 medicines in treating obesity Go to source) In 2025, the World Health Organization added GLP-1 therapies to its Essential Medicines List for selected high-risk adults with type 2 diabetes
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