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Table 8 Results of a 26-week Trial of Liraglutide Injection as Add-on to Metformin and Sulfonylurea in Adult Patients with Type 2 Diabetes Mellitus a Liraglutide Injection Compared to Exenatide, Both as Add-on to Metformin and/or Sulfonylurea Therapy In this 26-week, open-label trial, 464 adult patients with type 2 diabetes mellitus on a background of metformin monotherapy, sulfonylurea monotherapy or a combination of metformin and sulfonylurea were randomized to once daily liraglutide injection 1.8 mg or exenatide 10 mcg twice daily

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While GLP-1 receptor agonists (such as semaglutide and liraglutide) have demonstrated significant benefits in diabetes management, weight reduction, and cardiovascular outcomes in clinical trials, enhancing physiological GLP-1 through dietary and lifestyle modifications represents a foundational approach