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After the reaction was completed, an appropriate amount of a mixed solution of acetic anhydride and pyridine (volume ratio: Ac2O/Pyridine=7/6) was added to block the reaction for 5 h or more, following washing three times with DMF
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CagriSema produces higher rates of nausea (55% versus 31%) and vomiting (26% versus 12%) compared to tirzepatide in their respective clinical trials
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