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GLP-1R signalling promotes β-cell glucose metabolism via mTOR-dependent... | Download Scientific Diagram
A large Danish registry study published in 2020 found that individuals with type 2 diabetes treated with GLP-1 receptor agonists had a lower risk of dementia compared to those treated with other diabetes medications
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In terms of mechanism, GLP-1RAs may improve gut health by influencing gut motility, altering luminal pH, and changing bile acid metabolism, thereby encouraging the growth of beneficial bacteria and supporting the gut-brain-microbiome connection [7,21,22,24,25,35]
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