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Studies have demonstrated that GLP-1 receptor activation may reduce production of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and interleukin-1 beta (IL-1β) —the same inflammatory mediators that drive joint destruction in rheumatoid arthritis

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The other 80 women in the study, who were on tirzepatide alone, lost an average of 14 percent of their body weight