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Therefore, when estimated assuming 50% additivity, the HRs were 0.73 (95% CI 0.62–0.87) for MACE, 0.53 (95% CI, 0.41–0.70) for HHF, and 0.51 (95% CI, 0.38–0.68) for CKD progression
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Clinical trials reported no serious adverse events, with mostly mild to moderate side effects such as headache, dry mouth, and insomnia
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