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Covariates and Matching We identified potential confounders related to SIBO risk and the selection of T2DM therapy, including age at index, sex, BMI, HbA1C, hypertension, hyperlipidemia, atherosclerotic cardiovascular disease, hypothyroidism, medication such as opioids, proton pump inhibitors (PPI), etc

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Sudden inflammation of the pancreas may occur with these medications, though it is rare