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The kidney-protective effects of SGLT2is have been demonstrated in large randomized controlled trials (RCTs) with major kidney-specific primary end points ( e.g ., a composite of kidney failure, varying percent decline in eGFR, or death from kidney-related or cardiovascular causes)
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Glucose-Dependent Insulinotropic Polypeptide (GIP) Also excreted from intestinal K cells, GIP is a protein mostly postprandially secreted [25]
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