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Future research should focus on standardizing body composition assessments, evaluating long-term functional outcomes and exploring combinations of metabolic and muscle-targeted therapies

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In rats, administration of GLP-1R agonists into the hippocampus further prevented impairment of spatial learning and memory induced by central administration of amyloid β (Aβ), a protein considered to play a causative role in impairment of learning and memory in Alzheimer disease [832,833]