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approval in August 2025 for treatment of adults with noncirrhotic MASH and moderate-to-advanced liver fibrosis consistent with F2–F3 fibrosis

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'Clinical trials and newer imaging studies (DEXA, MRI) show that while people mainly lose fat mass, a proportion of the weight lost is lean tissue – mostly muscle and some bone mineral density,' says Dr Saima Ajaz, senior clinical lecturer at King’s College London and medical director at the Harley Weight Loss Clinic