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You may have read about eloralintide , an investigational medication Eli Lilly is developing that targets the amylin pathway instead of GLP-1 and showed strong weight loss in a Phase 2 trial reported in The Lancet
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K., et al., “Healthy Weight Loss Maintenance With Exercise, Liraglutide, or Both Combined,” New England Journal of Medicine 384 (2021): 1719–1730
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