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Mazdutide (IBI362), developed by Innovent Biologics with Eli Lilly China, is an oxyntomodulin analog that has progressed through seven Phase 3 trials and gained regulatory approval in China for type 2 diabetes
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The policy environment also matters: recent events—from the HRT warning removal (with its first approved label changes in February 2026) to the abandoned COVID vaccine boxed warning proposal, to new FDA guidances updating the 505(o)(4) framework—indicate that external pressures, scientific consensus, and political priorities all shape these ostensibly technical outcomes ( [30] ) ( [33] )
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