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4.4 Potential effects of tirzepatide on upper airway function In addition to metabolic and inflammatory modulation, emerging evidence suggests that incretin-based therapies may influence upper airway neuromuscular control
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A more recent and much larger multicenter, population-based study published yesterday in JAMA Ophthalmology has revealed an elevated inherent relative risk (incidence rate ratio, 1.32) of NAION for those exposed to semaglutide that’s much smaller than the 4.28-fold hazard ratio (HR) found in a study published last summer.1 This was a retrospective study across 14 databases (six administrative claims and eight electronic health records)
