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Similarly, the STEP 4 trial showed that participants who continued semaglutide treatment experienced an additional 7.9% reduction in body weight, while those switched to placebo despite lifestyle interventions gained 6.9% of their body weight over 12 months, demonstrating the importance of continued therapy for sustained weight management
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In the next part of this review, the diverse roles of GLP-1 in the depressive brain will be discussed
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