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Higher Relative Risk for Osteomalacia: The same AAOS study indicated that while rare, the relative risk for osteomalacia (bone softening) was more than double in the GLP-1 group
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Its most-studied use is in combination: co-administered with semaglutide (CagriSema), weight loss reached 15.6% at 32 weeks — far beyond semaglutide alone (5.1%)[2]
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