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Improvement and competition is expected over time, whether by creating more modifications to improve half-life , improving access to the brain, converting existing injectable drugs into oral forms, combining with other agonists or antagonists (Molecules that prevent receptors/molecules from functioning) such as DPP-4 inhibitors, which help extend the half-life of peptides such as GLP-1 and GIP
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He points to a clinical trial published in The New England Journal of Medicine studying the impact of semaglutide in people who were diagnosed with both overweight or obesity and heart disease, but who had no history of diabetes