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In a nitroglycerin-induced chronic migraine (CM) mouse model, GLP-1R expression was markedly increased and colocalized with microglia and astrocytes in the trigeminal nucleus caudalis (TNC) [94]
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Using NMRI mice, systemic Ex4 (2.4 ยตg/kg, i.p.) attenuated hyperlocomotion induced by cocaine (15 mg/kg, i.p.) and amphetamine (2 mg/kg, i.p.) and abolished drug-evoked increases in extracellular dopamine in the NAc, as assessed via in vivo microdialysis
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