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Brand-name Wegovy and Zepbound are worth the extra cost when you have insurance coverage that caps out-of-pocket at under $100 monthly, when you have a complex medical history that needs the exact dosing profile from the STEP 1 (Wilding et al., NEJM 2021) and SURMOUNT-1 (Jastreboff et al., NEJM 2022) trials, or when you're eligible for the Eli Lilly Direct or Novo Nordisk savings programs
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