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24 In this regard, prohormone convertase enzymes cleave proglucagon into several small peptides including glicentin, glicentin-related pancreatic polypeptide, glucagon, oxyntomodulin and GLP-1
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Related “incretin-based” medicines you might hear about include tirzepatide (Mounjaro for type 2 diabetes, and Zepbound for chronic weight management), a dual GIP/GLP-1 receptor agonist given as a once-weekly injection