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Treating diabetic mice with a GLP-1 agonist resulted in both ERK activation in nerve and protection against MNCV slowing, although at present we cannot conclude that the two are causally related
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Earlier this year, an FDA advisory committee recommended that two other DPP-4 inhibitors – AstraZeneca's (AZ) Onglyza (saxagliptin) and Takeda's Nesina (alogliptin) – should have their labels amended to indicate a possible increased risk of hospitalisation due to heart failure
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