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However, log ฯ c values for Asn-300 ECL2 โAla and Trp-306 5.36 โAla were not reduced, suggesting that the reduced potency of GLP-1 at these mutants could largely be accounted for by reduced GLP-1 affinity (Figure 3)
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Sermorelin can affect insulin sensitivity and glucose metabolism, which may require monitoring and adjustment of diabetes medications
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