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In a 6-month, randomized, double-blind, placebo-controlled trial of 98 overweight but otherwise healthy adults, 400mg/day of Morosil produced significantly greater reductions in body mass (4.2% vs
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GLP-1R can also suppress cardiac hypertrophy induced by Ang II through attenuating the Nox4-histone deacetylase 4 (HDAC4) axis [162]