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The lower-dose over-the-counter version sold in the United States as alli (approved by the FDA in 2007) has never been authorised for non-prescription sale in Canada

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These immune-mediated events were compounded by intolerable gastrointestinal side effects, including nausea in 59% and vomiting in 37% of participants, along with reports of acute pancreatitis, culminating in a dropout rate of 26–34% in Phase 3 trials [65]