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[4] [3] NICE recommends that GLP-1 receptor agonists should be reviewed after 6 months and only continued if the person has had a beneficial metabolic response (a reduction of at least 11 mmol/mol [1.0%] in HbA1c and weight loss of at least 3% of initial body weight)
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patients experiencing new or worsening joint symptoms should inform their GP or diabetes team [14] [20] Hepatic effects : Vildagliptin should be avoided in patients with hepatic impairment, and liver function tests should be monitored during treatment as specified in its SmPC
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