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The regulator went against the recommendation of its Pulmonary-Allergy Drugs Advisory Committee (PADAC), which in May voted 16-6 in favor of the treatment in adults and 17-5 in kids 18 years and younger
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Low doses of peripheral Ex-4 (0.1 and 0.2 μg/kg) reduced cocaine priming-induced reinstatement of cocaine-seeking behavior dose-dependently but did not affect chow food intake, meal patterns, and body weight (Hernandez et al., 2018, 2019)