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5 Molecular and physiological mechanisms 5.1 Receptor signalling and tissue-level biology The GLP-1 receptor is a class B G-protein-coupled receptor that signals predominantly through Gs-mediated activation of adenylyl cyclase, cyclic AMP, protein kinase A and EPAC (16–18)
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Efficacy and safety of once-weekly glucagon-like peptide 1 receptor agonists for the management of type 2 diabetes:a systematic review and meta-analysis of randomized controlled trials
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