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found two patients with deletions in NPAP1, SNURF-SNRPN, and the SNORD genes, who exhibited major clinical signs of PWS, including obesity ( In summary, although data linking genotype and obesity in human studies is limited, these findings underscore the importance of taking a comprehensive approach to studying phenotypes throughout life

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Diabetes Ther 14(4):777–786 [DOI] [PMC free article] [PubMed] [Google Scholar] 34.Ceasovschih A, Asaftei A, Lupo MG, Kotlyarov S, Bartuskova H, Balta A et al (2025) Glucagon-like peptide-1 receptor agonists and muscle mass effects