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This National Psoriasis Foundation primer, published in JAMA Dermatology, provides dermatologists and rheumatologists with a practical framework for understanding GLP-1 RA pharmacology, their landmark cardiovascular, metabolic, and organ-protection trial data, the emerging evidence base for psoriasis-specific benefit, and a clinical guide to agent selection, dosing, and safety monitoring in patients with psoriasis

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pharmacokinetic data show bupropion SR peaks around 3 hours (StatPearls)