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서울의대 조영민 교수는 "중추신경계에 작용하는 약물이 가진 큰 문제는 의존성"이라며 "반면에 GLP-1 제제는 그런 문제가 없고, 다만 초기에 발생하는 구역, 구토 증상을 잘 넘기면 비교적 높은 체중 감량효과를 얻을 수 있다"고 평가했다
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