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The PP1-R6 protein phosphatase holoenzyme is involved in the glucose-induced dephosphorylation and inactivation of AMP-activated protein kinase, a key regulator of insulin secretion, in MIN6 beta cells
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However, developing fit-for-purpose cell-based nAb assays present multiple challenges, especially when excessive drug level in patient samples interferes with nAb detection and decreases assay sensitivity [3]
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