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In addition, chimeric GLP-2 whose C-terminal fragment (residues 20–33) was replaced with that of GLP-1 displayed a 17-fold potency reduction in GLP-2R signaling but successfully elicited GLP-1R-mediated cAMP accumulation (Fig
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GLP-1 receptor agonists have transformed the management of obesity and type 2 diabetes in recent years
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