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Retatrutide's glucagon activity adds small, dose-related increases in heart rate and glucose seen in trials
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They also produce glucose-dependent insulinotropic peptide (GIP), which has an incretin effect like that of GLP-1, the motility hormones (motilin and serotonin), and other hormones such as secretin (SCT) and GLP-2, which regulate digestion and intestinal homeostasis [13]
