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Their effects on the individual components of MACE, myocardial infarction (reduced in LEADER and Harmony Outcomes), and stroke (reduced in SUSTAIN-6 and REWIND), varied in each trial (Table 1)
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ACAA2 is involved in mitochondrial fatty acid-β oxidation [29], whereas GSTK1 is critical for maintaining mitochondrial homeostasis [30]
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