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Compared with the saline group, the physiological dose of GLP-1 injected during the hyperglycemic clamp can significantly reduce the glucagon level in post-transplantation diabetic patients, suggesting that GLP-1 has a clear glucagon inhibitory effect and can restore the altered insulin and glucagon secretion in post-transplantation diabetic patients in a glucose-dependent manner (Halden et al., 2016)
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