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No braço de 12 mg, os participantes seguiram um esquema de escalada por etapas: Dose inicial: 2 mg uma vez por semana Escalada: doses mais elevadas introduzidas a intervalos de 4 semanas Dose-alvo: 12 mg uma vez por semana Este esquema foi utilizado num contexto de ensaio clínico

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Efficacy and Safety of Varenicline for Smoking Cessation in Patients With Type 2 Diabetes: A Randomized Clinical Trial