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Although seemingly contradictory, both GIP agonism, as seen with tirzepatide, and GIP antagonism, as observed with MariTide, have shown to synergise with GLP-1R agonism to promote remarkable weight loss[105]

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Common Adverse Reactions Table 2 shows common adverse reactions, excluding hypoglycemia, associated with the use of semaglutide tablets in adult patients with type 2 diabetes mellitus in the pool of placebo-controlled trials