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There is no strict clinical definition of short-term GLP-1 use, and duration will depend on individual goals, tolerability, rate of progress, and prescriber guidance
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Disruption of this interface using either peptides derived from the sequence of TM4, or site-directed mutagenesis of Gly 243 and Ile 244 , demonstrated that the oligomerization mediated by the lipid-exposed face of TM4 was important for the full potency of secretin
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